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eef1g eukaryotic translation elongation factor 1 gamma [ Danio rerio (zebrafish) ]

Gene ID: 195822, updated on 4-Jan-2025

Summary

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Official Symbol
eef1gprovided by ZNC
Official Full Name
eukaryotic translation elongation factor 1 gammaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020423-3
See related
Ensembl:ENSDARG00000056119 AllianceGenome:ZFIN:ZDB-GENE-020423-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
db03h10; fk76a09; mg:db03h10; wu:fk76a09
Summary
Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See eef1g in Genome Data Viewer
Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (26719740..26729289)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (26421635..26431184)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene neurogenin 1 Neighboring gene RNA polymerase II subunit G Neighboring gene AHNAK nucleoprotein Neighboring gene kelch-like family member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Burket CT, et al. Transgenic Res, 2008 Apr. PMID 17968670, Free PMC Article
  2. Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing. Nepal C, et al. Nat Commun, 2020 Jan 10. PMID 31924754, Free PMC Article
  3. Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model. Yang Z, et al. Biotechnol Lett, 2018 Dec. PMID 30244429, Free PMC Article
  4. Control of cranial ectomesenchyme fate by Nr2f nuclear receptors. Okeke C, et al. Development, 2022 Dec 1. PMID 36367707, Free PMC Article
  5. Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model. Li Y, et al. Dis Model Mech, 2019 Oct 17. PMID 31515263, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
elongation factor 1-gamma
Names
EF-1-gamma
eEF-1B gamma
nan
nearly normal

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173263.1 → NP_775370.1  elongation factor 1-gamma

    See identical proteins and their annotated locations for NP_775370.1

    Status: PROVISIONAL

    Source sequence(s)
    AY099512
    UniProtKB/Swiss-Prot
    Q6PE25
    UniProtKB/TrEMBL
    Q8JIU6
    Related
    ENSDARP00000072983.4, ENSDART00000078522.6
    Conserved Domains (4) summary
    cd03181
    Location:91 → 213
    GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins
    cd03044
    Location:4 → 82
    GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...
    TIGR01262
    Location:5 → 201
    maiA; maleylacetoacetate isomerase
    pfam00647
    Location:280 → 386
    EF1G; Elongation factor 1 gamma, conserved domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    26719740..26729289
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PE25.1 GenPept UniProtKB/Swiss-Prot:Q6PE25

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