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Vmn2r129 vomeronasal 2, receptor 129 [ Mus musculus (house mouse) ]

Gene ID: 22314, updated on 27-Nov-2024

Summary

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Official Symbol
Vmn2r129provided by MGI
Official Full Name
vomeronasal 2, receptor 129provided by MGI
Primary source
MGI:MGI:1316735
See related
Ensembl:ENSMUSG00000057021 AllianceGenome:MGI:1316735
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
V2r8; V2r9; Vmn2r-ps159; Vmn2r-ps160
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Vmn2r129 in Genome Data Viewer
Location:
4; 4 E2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (156683398..156691794)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (156331103..156339499)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor, 122 Neighboring gene predicted gene, 53275 Neighboring gene vomeronasal 2, receptor 125

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. FGF signalling controls expression of vomeronasal receptors during embryogenesis. Lioubinski O, et al. Mech Dev, 2006 Jan. PMID 16326081
  2. Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene. Göllner H, et al. Genes Cells, 2001 Aug. PMID 11532028
  3. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal 2, receptor 129
Names
vomeronasal 2, receptor, 8
vomeronasal 2, receptor, 9
vomeronasal 2, receptor, pseudogene 159
vomeronasal 2, receptor, pseudogene 160
vomeronasal organ family 2, receptor, 8
vomeronasal organ family 2, receptor, 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384510.1 → NP_001371439.1  vomeronasal 2, receptor 129 precursor

    Status: VALIDATED

    Source sequence(s)
    FP885536
    UniProtKB/TrEMBL
    A0A494B975, O35201
    Related
    ENSMUSP00000157509.2, ENSMUST00000074107.13
    Conserved Domains (1) summary
    cl10011
    Location:46 → 432
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

RNA

  1. NR_038052.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AF011418, AF011419
    Related
    ENSMUST00000189559.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    156683398..156691794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163981.1 → XP_036019874.1  vomeronasal 2, receptor 129 isoform X2

    UniProtKB/TrEMBL
    A0A3Q4EIC8
    Conserved Domains (3) summary
    cd15283
    Location:582 → 832
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:46 → 500
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:508 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  2. XM_036163980.1 → XP_036019873.1  vomeronasal 2, receptor 129 isoform X1

    UniProtKB/TrEMBL
    A0A3Q4EIC8
    Related
    ENSMUSP00000157307.2, ENSMUST00000096792.8
    Conserved Domains (3) summary
    cd15283
    Location:581 → 831
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:46 → 500
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:508 → 561
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  3. XM_036163982.1 → XP_036019875.1  vomeronasal 2, receptor 129 isoform X3

    UniProtKB/TrEMBL
    O35201
    Conserved Domains (1) summary
    cl10011
    Location:46 → 431
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_009494.1: Suppressed sequence

    Description
    NM_009494.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.

  2. NM_009495.1: Suppressed sequence

    Description
    NM_009495.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein Strain
Heading Accession and Version

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