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Timm8a2 translocase of inner mitochondrial membrane 8A2 [ Mus musculus (house mouse) ]

Gene ID: 223262, updated on 27-Nov-2024

Summary

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Official Symbol
Timm8a2provided by MGI
Official Full Name
translocase of inner mitochondrial membrane 8A2provided by MGI
Primary source
MGI:MGI:3615492
See related
Ensembl:ENSMUSG00000071229 AllianceGenome:MGI:3615492
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in protein transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 2.0) and thymus adult (RPKM 0.1) See more
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Genomic context

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See Timm8a2 in Genome Data Viewer
Location:
14 E5; 14 65.86 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (122265089..122275834)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (122027677..122038422)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ubiquitin associated domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E7358 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122327665-122327966 Neighboring gene STARR-positive B cell enhancer ABC_E8579 Neighboring gene predicted gene, 46485 Neighboring gene G protein-coupled receptor 18 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122337770-122338071 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122364300-122364601 Neighboring gene G protein-coupled receptor 183 Neighboring gene predicted gene, 52103 Neighboring gene STARR-positive B cell enhancer ABC_E8580 Neighboring gene STARR-positive B cell enhancer ABC_E4126 Neighboring gene STARR-positive B cell enhancer ABC_E4127 Neighboring gene STARR-positive B cell enhancer ABC_E8581 Neighboring gene STARR-positive B cell enhancer ABC_E5466 Neighboring gene RIKEN cDNA A330035P11 gene Neighboring gene STARR-positive B cell enhancer ABC_E5467 Neighboring gene transmembrane 9 superfamily member 2 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC117751

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
putative mitochondrial import inner membrane translocase subunit Tim8 A-B
Names
translocase of inner mitochondrial membrane 8 homolog a2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037744.1 → NP_001032833.1  putative mitochondrial import inner membrane translocase subunit Tim8 A-B

    See identical proteins and their annotated locations for NP_001032833.1

    Status: PROVISIONAL

    Source sequence(s)
    BC099499
    Consensus CDS
    CCDS37020.1
    UniProtKB/Swiss-Prot
    Q4FZG7
    Related
    ENSMUSP00000047497.7, ENSMUST00000045976.7
    Conserved Domains (1) summary
    pfam02953
    Location:21 → 83
    zf-Tim10_DDP; Tim10/DDP family zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    122265089..122275834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518919.4 → XP_006518982.1  putative mitochondrial import inner membrane translocase subunit Tim8 A-B isoform X1

    See identical proteins and their annotated locations for XP_006518982.1

    UniProtKB/Swiss-Prot
    Q4FZG7
    Conserved Domains (1) summary
    pfam02953
    Location:21 → 83
    zf-Tim10_DDP; Tim10/DDP family zinc finger
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4FZG7.1 GenPept UniProtKB/Swiss-Prot:Q4FZG7

Gene LinkOut

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