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Cryzl2 crystallin zeta like 2 [ Mus musculus (house mouse) ]

Gene ID: 226527, updated on 4-Jan-2025

Summary

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Official Symbol
Cryzl2provided by MGI
Official Full Name
crystallin zeta like 2provided by MGI
Primary source
MGI:MGI:2448516
See related
Ensembl:ENSMUSG00000033488 AllianceGenome:MGI:2448516
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable oxidoreductase activity. Located in mitochondrion. Orthologous to human CRYZL2P (crystallin zeta like 2, pseudogene). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in kidney adult (RPKM 78.4), adrenal adult (RPKM 11.4) and 7 other tissues See more
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Genomic context

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See Cryzl2 in Genome Data Viewer
Location:
1 H1; 1 67.99 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (157280082..157317570)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (157455718..157490000)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RAS protein activator like 2 Neighboring gene RIKEN cDNA 2810025M15 gene Neighboring gene STARR-positive B cell enhancer ABC_E5829 Neighboring gene STARR-seq mESC enhancer starr_02765 Neighboring gene GABA(A) receptor-associated protein-like 2 pseudogene 1_1522.1 Neighboring gene STARR-seq mESC enhancer starr_02769 Neighboring gene STARR-seq mESC enhancer starr_02770 Neighboring gene predicted gene, 57801 Neighboring gene predicted gene 15486 Neighboring gene SEC16 homolog B, endoplasmic reticulum export factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of new ciliary signaling pathways in the brain and insights into neurological disorders. Loukil A, et al. bioRxiv, 2023 Dec 21. PMID 38187761, Free PMC Article
  2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
quinone oxidoreductase-like protein 2
Names
quinone reductase-like 2
zeta-crystallin homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033284.3 → NP_001028456.1  quinone oxidoreductase-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001028456.1

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108
    Consensus CDS
    CCDS15399.1
    UniProtKB/Swiss-Prot
    Q3UAM2, Q3UNZ8
    Related
    ENSMUSP00000044945.5, ENSMUST00000046743.11
    Conserved Domains (1) summary
    cd08241
    Location:27 → 347
    QOR1; Quinone oxidoreductase (QOR)

  2. NM_001356418.2 → NP_001343347.1  quinone oxidoreductase-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108
    Consensus CDS
    CCDS87898.1
    UniProtKB/TrEMBL
    A0A0A6YWV6
    Related
    ENSMUSP00000141717.2, ENSMUST00000193791.6
    Conserved Domains (1) summary
    cl16912
    Location:27 → 169
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

  3. NM_001356419.2 → NP_001343348.1  quinone oxidoreductase-like protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108
    Consensus CDS
    CCDS87899.1
    Related
    ENSMUSP00000113664.2, ENSMUST00000119891.7
    Conserved Domains (1) summary
    cl16912
    Location:27 → 167
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

  4. NM_001421427.1 → NP_001408356.1  quinone oxidoreductase-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108

  5. NM_001421432.1 → NP_001408361.1  quinone oxidoreductase-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108

  6. NM_001421433.1 → NP_001408362.1  quinone oxidoreductase-like protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108

  7. NM_001421434.1 → NP_001408363.1  quinone oxidoreductase-like protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108

  8. NM_001421435.1 → NP_001408364.1  quinone oxidoreductase-like protein 2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC119897, AC161108

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    157280082..157317570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164051.1 → XP_036019944.1  quinone oxidoreductase-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q3UAM2, Q3UNZ8
    Conserved Domains (1) summary
    cd08241
    Location:27 → 347
    QOR1; Quinone oxidoreductase (QOR)

  2. XM_017319995.1 → XP_017175484.1  quinone oxidoreductase-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q3UAM2, Q3UNZ8
    Conserved Domains (1) summary
    cd08241
    Location:27 → 347
    QOR1; Quinone oxidoreductase (QOR)

  3. XM_030253320.1 → XP_030109180.1  quinone oxidoreductase-like protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0A6YWV6
    Conserved Domains (1) summary
    cl16912
    Location:27 → 169
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

  4. XM_030253318.1 → XP_030109178.1  quinone oxidoreductase-like protein 2 isoform X2

    Conserved Domains (1) summary
    cd08241
    Location:27 → 252
    QOR1; Quinone oxidoreductase (QOR)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UNZ8.1 GenPept UniProtKB/Swiss-Prot:Q3UNZ8

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