MCF2L - MCF.2 cell line derived transforming sequence like
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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