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Zfp940 zinc finger protein 940 [ Mus musculus (house mouse) ]

Gene ID: 233057, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp940provided by MGI
Official Full Name
zinc finger protein 940provided by MGI
Primary source
MGI:MGI:2446235
See related
Ensembl:ENSMUSG00000050855 AllianceGenome:MGI:2446235
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 3.0), cerebellum adult (RPKM 2.4) and 17 other tissues See more
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Genomic context

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See Zfp940 in Genome Data Viewer
Location:
7 B1; 7 17.26 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29533943..29553101, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29832361..29853695, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18490 Neighboring gene predicted gene 6579 Neighboring gene STARR-seq mESC enhancer starr_18491 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:30601028-30601137 Neighboring gene zinc finger protein 790 Neighboring gene STARR-positive B cell enhancer ABC_E8836 Neighboring gene STARR-positive B cell enhancer ABC_E10434 Neighboring gene zinc finger protein 420 Neighboring gene STARR-seq mESC enhancer starr_18494 Neighboring gene zinc finger protein 27 Neighboring gene microRNA 7668

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 940

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419283.1 → NP_001406212.1  zinc finger protein 940 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC156934
    UniProtKB/TrEMBL
    Q8R2Q3

  2. NM_001419284.1 → NP_001406213.1  zinc finger protein 940 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC156934
    UniProtKB/TrEMBL
    Q8R2Q3

  3. NM_001419285.1 → NP_001406214.1  zinc finger protein 940 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC156934
    UniProtKB/TrEMBL
    Q3UVK2
    Related
    ENSMUSP00000103858.2, ENSMUST00000108223.8

  4. NM_173738.3 → NP_776099.1  zinc finger protein 940 isoform 1

    See identical proteins and their annotated locations for NP_776099.1

    Status: VALIDATED

    Source sequence(s)
    AC156934
    Consensus CDS
    CCDS39873.1
    UniProtKB/TrEMBL
    Q3V1P9, Q8R2Q3
    Related
    ENSMUSP00000082947.5, ENSMUST00000085792.5
    Conserved Domains (4) summary
    smart00349
    Location:6 → 66
    KRAB; krueppel associated box
    COG5048
    Location:249 → 437
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:398 → 418
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:342 → 357
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    29533943..29553101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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