Prr12 proline rich 12 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Prr12provided by MGI
Official Full Name: proline rich 12provided by MGI
Primary source: MGI:MGI:2679002
See related: Ensembl:ENSMUSG00000046574 AllianceGenome:MGI:2679002
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 6720469B10
Summary: Predicted to enable DNA binding activity. Predicted to be located in neuron projection; nucleus; and postsynaptic density. Is expressed in central nervous system and retina. Orthologous to human PRR12 (proline rich 12). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in thymus adult (RPKM 11.0), adrenal adult (RPKM 9.5) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B3; 7 29.08 cM

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (44677125..44702758, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (45027701..45053334, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in postsynaptic density	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: proline-rich protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175022.3 → NP_778187.2 proline-rich protein 12

Status: VALIDATED

Source sequence(s)

AC126256

Consensus CDS

CCDS52241.1

UniProtKB/Swiss-Prot

E9PYL2, Q69ZN8

Related

ENSMUSP00000054702.7, ENSMUST00000057293.8

Conserved Domains (1) summary

pfam13926
Location:1827 → 1950

DUF4211; Domain of unknown function (DUF4211)