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Lman1l lectin, mannose-binding 1 like [ Mus musculus (house mouse) ]

Gene ID: 235416, updated on 27-Nov-2024

Summary

Official Symbol
Lman1lprovided by MGI
Official Full Name
lectin, mannose-binding 1 likeprovided by MGI
Primary source
MGI:MGI:2667537
See related
Ensembl:ENSMUSG00000056271 AllianceGenome:MGI:2667537
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
slamp
Summary
Predicted to enable D-mannose binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in metanephros and submandibular gland. Orthologous to human LMAN1L (lectin, mannose binding 1 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Lman1l in Genome Data Viewer
Location:
9 B; 9 31.13 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57514080..57528057, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57607033..57620774, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene unc-51-like kinase 3 Neighboring gene complexin 3 Neighboring gene predicted gene, 32392 Neighboring gene c-src tyrosine kinase Neighboring gene STARR-positive B cell enhancer ABC_E9763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:57498764-57498965 Neighboring gene cytochrome P450, family 1, subfamily a, polypeptide 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC28923

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables D-mannose binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein ERGIC-53-like
Names
ERGIC53-like protein
LMAN1-like protein
sublingual acinar membrane protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199222.3NP_954692.2  protein ERGIC-53-like precursor

    See identical proteins and their annotated locations for NP_954692.2

    Status: VALIDATED

    Source sequence(s)
    AB211986, AC122528, BY708954
    Consensus CDS
    CCDS52810.1
    UniProtKB/Swiss-Prot
    Q4H2F4, Q8VCD3
    Related
    ENSMUSP00000091352.5, ENSMUST00000093832.11
    Conserved Domains (1) summary
    cd06902
    Location:32255
    lectin_ERGIC-53_ERGL; ERGIC-53 and ERGL type 1 transmembrane proteins, N-terminal lectin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    57514080..57528057 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154901.1XP_036010794.1  protein ERGIC-53-like isoform X1