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tin-9.2 Mitochondrial import inner membrane translocase subunit Tim10B [ Caenorhabditis elegans ]

Gene ID: 24105311, updated on 9-Dec-2024

Summary

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Official Symbol
tin-9.2
Official Full Name
Mitochondrial import inner membrane translocase subunit Tim10B
Primary source
WormBase:WBGene00044083
Locus tag
CELE_TIN-9.2
See related
AllianceGenome:WB:WBGene00044083
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metal ion binding activity. Involved in inductive cell migration and regulation of growth. Located in mitochondrion. Orthologous to human TIMM10B (translocase of inner mitochondrial membrane 10B). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See tin-9.2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (13099005..13100582)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SAP domain-containing protein Neighboring gene Replication factor C subunit 3 Neighboring gene Dynein light intermediate chain Neighboring gene Putative exosome complex component RRP41 Neighboring gene RAP domain-containing protein Neighboring gene RNA interference defective protein 11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development. Curran SP, et al. J Biol Chem, 2004 Dec 24. PMID 15485840
  2. The effects of plant cysteine proteinases on the nematode cuticle. Njom VS, et al. Parasit Vectors, 2021 Jun 5. PMID 34090505, Free PMC Article
  3. Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative diseases. Kirstein-Miles J, et al. Dev Dyn, 2010 May. PMID 20419784, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in inductive cell migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in reproductive process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mitochondrial import inner membrane translocase subunit Tim10B
NP_001368153.1
  • Partially confirmed by transcript evidence
NP_001379430.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13099005..13100582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392423.1 → NP_001379430.1  Mitochondrial import inner membrane translocase subunit Tim10B [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5FC56, Q9Y0V2
    Conserved Domains (1) summary
    pfam02953
    Location:4 → 63
    zf-Tim10_DDP; Tim10/DDP family zinc finger

  2. NM_001380504.1 → NP_001368153.1  Mitochondrial import inner membrane translocase subunit Tim10B [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    J7SF95
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y0V2.1

Gene LinkOut

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Molecular Biology Databases
Research Materials