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Ttc34 tetratricopeptide repeat domain 34 [ Mus musculus (house mouse) ]

Gene ID: 242800, updated on 27-Nov-2024

Summary

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Official Symbol
Ttc34provided by MGI
Official Full Name
tetratricopeptide repeat domain 34provided by MGI
Primary source
MGI:MGI:2445205
See related
Ensembl:ENSMUSG00000046637 AllianceGenome:MGI:2445205
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4932418L02; B230396O12Rik
Summary
Orthologous to human TTC34 (tetratricopeptide repeat domain 34). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 8.1), ovary adult (RPKM 3.5) and 1 other tissue See more
Orthologs
human all
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Genomic context

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See Ttc34 in Genome Data Viewer
Location:
4 E2; 4 85.47 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (154921871..154951582)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (154837308..154867125)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13110 Neighboring gene STARR-seq mESC enhancer starr_12237 Neighboring gene actin-related protein T2 Neighboring gene VISTA enhancer mm1492 Neighboring gene STARR-seq mESC enhancer starr_12238 Neighboring gene VISTA enhancer mm1088 Neighboring gene VISTA enhancer mm1090 Neighboring gene STARR-positive B cell enhancer ABC_E6294 Neighboring gene STARR-seq mESC enhancer starr_12240 Neighboring gene STARR-positive B cell enhancer ABC_E2734 Neighboring gene predicted gene 13112 Neighboring gene STARR-positive B cell enhancer ABC_E847 Neighboring gene membrane metallo-endopeptidase-like 1 Neighboring gene peroxiredoxin like 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  2. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
tetratricopeptide repeat protein 34
Names
TPR repeat protein 34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172878.4 → NP_766466.4  tetratricopeptide repeat protein 34

    Status: VALIDATED

    Source sequence(s)
    AL607032
    Consensus CDS
    CCDS19015.2
    UniProtKB/TrEMBL
    A0A140LHH0
    Related
    ENSMUSP00000146409.2, ENSMUST00000207854.2
    Conserved Domains (2) summary
    TIGR02917
    Location:543 → 920
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:675 → 703
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    154921871..154951582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320227.3 → XP_017175716.1  tetratricopeptide repeat protein 34 isoform X1

    Conserved Domains (1) summary
    sd00006
    Location:674 → 704
    TPR; TPR repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C0Q3.2 GenPept UniProtKB/Swiss-Prot:Q8C0Q3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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