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Defb13 defensin beta 13 [ Mus musculus (house mouse) ]

Gene ID: 246083, updated on 27-Nov-2024

Summary

Official Symbol
Defb13provided by MGI
Official Full Name
defensin beta 13provided by MGI
Primary source
MGI:MGI:2179203
See related
Ensembl:ENSMUSG00000044222 AllianceGenome:MGI:2179203
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BD-13
Summary
Predicted to enable lipid binding activity. Predicted to be involved in defense response to bacterium. Predicted to be located in extracellular region. Orthologous to human DEFB107A (defensin beta 107A) and DEFB107B (defensin beta 107B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward genital fat pad adult (RPKM 2.0) See more
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Genomic context

See Defb13 in Genome Data Viewer
Location:
8 A2; 8 10.68 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22436771..22438866)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (21946755..21948622)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36879 Neighboring gene defensin beta 15 Neighboring gene defensin beta 35 Neighboring gene predicted gene, 29821 Neighboring gene STARR-seq mESC enhancer starr_20895 Neighboring gene family with sequence similarity 90, member A1A Neighboring gene coiled-coil domain containing 70

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139223.5NP_631969.1  beta-defensin 13 precursor

    See identical proteins and their annotated locations for NP_631969.1

    Status: VALIDATED

    Source sequence(s)
    AL590619
    Consensus CDS
    CCDS40290.1
    UniProtKB/Swiss-Prot
    A2A4E3, Q8R2I4
    Related
    ENSMUSP00000060997.4, ENSMUST00000060587.4
    Conserved Domains (1) summary
    pfam13841
    Location:3058
    Defensin_beta_2; Beta defensin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    22436771..22438866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)