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CG30031 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246404, updated on 2-Nov-2024

Summary

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Official Symbol
CG30031provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050031
Locus tag
Dmel_CG30031
See related
AllianceGenome:FB:FBgn0050031
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG30031; endo-I; SP6
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in gastric caecum. Orthologous to human PRSS36 (serine protease 36) and PRSS53 (serine protease 53). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CG30031 in Genome Data Viewer
Location:
47F4-47F4; 2-64 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11350811..11351621)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7238316..7239126)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene betaTrypsin Neighboring gene gammaTrypsin Neighboring gene uncharacterized protein Neighboring gene deltaTrypsin Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Study on the material basis and mechanism of Hemerocallis citrina Baroni on sleep-improvement using Drosophila activity monitoring, metabolomic, targeted screening and transcriptomic. Liang Y, et al. Food Res Int, 2023 Oct. PMID 37689837
  2. Protease gene duplication and proteolytic activity in Drosophila female reproductive tracts. Kelleher ES, et al. Mol Biol Evol, 2009 Sep. PMID 19546158, Free PMC Article
  3. Intellectual disability-associated dBRWD3 regulates gene expression through inhibition of HIRA/YEM-mediated chromatin deposition of histone H3.3. Chen WY, et al. EMBO Rep, 2015 Apr. PMID 25666827, Free PMC Article
  4. A novel interplay between the ubiquitin–proteasome system and serine proteases during Drosophila development. Lipinszki Z, et al. Biochem J, 2013 Sep 15. PMID 23805892
  5. Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. Nakano S, et al. PLoS Genet, 2023 Jun. PMID 37319131, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The purification, identification and characterization of a novel protease (endoproteinase I) from Drosophila melanogaster.
    Title: A novel interplay between the ubiquitin–proteasome system and serine proteases during Drosophila development.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG30031-PA
endoproteinase I
NP_725035.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    11350811..11351621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165824.3 → NP_725035.1  uncharacterized protein Dmel_CG30031 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725035.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0HKA2, C0HKA3, C0HKA4, G7H855, P42276, P42277, Q8SXZ4, Q9V5Y4
    UniProtKB/TrEMBL
    G2J5V1
    Related
    FBpp0087224
    Conserved Domains (1) summary
    smart00020
    Location:30 → 249
    Tryp_SPc; Trypsin-like serine protease
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C0HKA2.1
C0HKA3.1
C0HKA4.1 C0HKA4

Gene LinkOut

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