U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MFS1 Major Facilitator Superfamily Transporter 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246519, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
MFS1provided by FlyBase
Official Full Name
Major Facilitator Superfamily Transporter 1provided by FlyBase
Primary source
FLYBASE:FBgn0050272
Locus tag
Dmel_CG30272
See related
AllianceGenome:FB:FBgn0050272
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11682; CG30272; Dmel\CG30272
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MFS1 in Genome Data Viewer
Location:
59B2-59B2; 2-101 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22829644..22831877)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18717167..18719400)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
  2. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. Colca JR, et al. PLoS One, 2013. PMID 23690925, Free PMC Article
  3. Survival Rate and Transcriptional Response upon Infection with the Generalist Parasite Beauveria bassiana in a World-Wide Sample of Drosophila melanogaster. Paparazzo F, et al. PLoS One, 2015. PMID 26154519, Free PMC Article
  4. Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling. Erkosar B, et al. PLoS One, 2014. PMID 24733183, Free PMC Article
  5. The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network. Känel P, et al. Aging (Albany NY), 2022 Apr 8. PMID 35396341, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
major facilitator superfamily transporter 1
Names
CG30272-PA
MFS1-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22829644..22831877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166564.2 → NP_726254.1  major facilitator superfamily transporter 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726254.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MMD6
    Related
    FBpp0071801
    Conserved Domains (2) summary
    cd06174
    Location:18 → 444
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:19 → 456
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MMD6 Q8MMD6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous