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CG30275 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246522, updated on 4-Jan-2025

Summary

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Official Symbol
CG30275provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050275
Locus tag
Dmel_CG30275
See related
AllianceGenome:FB:FBgn0050275
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13520; Dmel\CG30275
Summary
Predicted to enable oxidoreductase activity. Predicted to be involved in sperm flagellum assembly. Predicted to be active in sperm flagellum. Is expressed in spermatogonium. Human ortholog(s) of this gene implicated in spermatogenic failure 84. Orthologous to human CFAP61 (cilia and flagella associated protein 61). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG30275 in Genome Data Viewer
Location:
59A3-59A3; 2-101 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22707794..22712724)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18595299..18600229)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43735 Neighboring gene Odorant-binding protein 58c Neighboring gene Odorant-binding protein 58d Neighboring gene uncharacterized protein Neighboring gene jitterbug Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599819, Free PMC Article
  2. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  3. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
  4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in sperm flagellum assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30275-PL
CG30275-PM
CG30275-PN
NP_001137738.2
NP_726231.4
NP_788430.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22707794..22712724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176250.4 → NP_788430.3  uncharacterized protein Dmel_CG30275, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788430.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KVK5
    Conserved Domains (1) summary
    pfam16092
    Location:5 → 279
    DUF4821; Domain of unknown function (DUF4821)

  2. NM_166544.4 → NP_726231.4  uncharacterized protein Dmel_CG30275, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726231.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MME7
    Conserved Domains (1) summary
    pfam16092
    Location:5 → 266
    DUF4821; Domain of unknown function (DUF4821)

  3. NM_001144266.2 → NP_001137738.2  uncharacterized protein Dmel_CG30275, isoform N [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137738.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZN9
    Conserved Domains (1) summary
    pfam16092
    Location:5 → 266
    DUF4821; Domain of unknown function (DUF4821)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7YZN9 B7YZN9
Q7KVK5 Q7KVK5
Q8MME7 Q8MME7
Q8MZE1 Q8MZE1

Gene LinkOut

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