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CG30323 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246539, updated on 9-Dec-2024

Summary

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Official Symbol
CG30323provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050323
Locus tag
Dmel_CG30323
See related
AllianceGenome:FB:FBgn0050323
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11430; Dmel\CG30323; olf186; SPH206
Summary
Predicted to be involved in innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG30323 in Genome Data Viewer
Location:
54F1-54F1; 2-84 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17853295..17854296)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13740800..13741801)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45270 Neighboring gene grainy head Neighboring gene olf186-M Neighboring gene orai Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44417 Neighboring gene mapmodulin Neighboring gene three rows

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Compartmentalized calcium transients trigger dendrite pruning in Drosophila sensory neurons. Kanamori T, et al. Science, 2013 Jun 21. PMID 23722427
  2. Enhanced function annotations for Drosophila serine proteases: a case study for systematic annotation of multi-member gene families. Shah PK, et al. Gene, 2008 Jan 15. PMID 17996400
  3. Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Ross J, et al. Gene, 2003 Jan 30. PMID 12568721
  4. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
NOT enables peptidase activity IKR
Inferred from Key Residues
more info
  
NOT enables serine-type endopeptidase activity IKR
Inferred from Key Residues
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30323-PB
CG30323-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17853295..17854296
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166256.3 → NP_725729.2  uncharacterized protein Dmel_CG30323, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725729.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZB07
    Conserved Domains (2) summary
    smart00020
    Location:45 → 272
    Tryp_SPc; Trypsin-like serine protease
    cl21584
    Location:45 → 275
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  2. NM_001274135.1 → NP_001261064.1  uncharacterized protein Dmel_CG30323, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261064.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KFB1
    Conserved Domains (2) summary
    smart00020
    Location:45 → 247
    Tryp_SPc; Trypsin-like serine protease
    cl21584
    Location:45 → 250
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KFB1 A0A0B4KFB1
A1ZB07 A1ZB07

Gene LinkOut

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