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CG30339 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246549, updated on 9-Dec-2024

Summary

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Official Symbol
CG30339provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050339
Locus tag
Dmel_CG30339
See related
AllianceGenome:FB:FBgn0050339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE54230; Dmel\CG30339
Summary
Predicted to enable lipid transfer activity and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG30339 in Genome Data Viewer
Location:
45F6-45F6; 2-61 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9601431..9602901, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5488936..5490406, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene closca Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44285 Neighboring gene Glutathione S transferase T1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N, et al. Development, 2014 Oct. PMID 25294943, Free PMC Article
  2. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
  3. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  4. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article
  5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables lipid transfer activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatidylinositol bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in intermembrane lipid transfer ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in late endosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30339-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9601431..9602901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165687.3 → NP_724813.1  uncharacterized protein Dmel_CG30339 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724813.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXR4
    Related
    FBpp0087617
    Conserved Domains (2) summary
    smart01100
    Location:28 → 70
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:109 → 250
    CRAL_TRIO; CRAL/TRIO domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SXR4 Q8SXR4

Gene LinkOut

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