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GstE9 Glutathione S transferase E9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246581, updated on 9-Dec-2024

Summary

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Official Symbol
GstE9provided by FlyBase
Official Full Name
Glutathione S transferase E9provided by FlyBase
Primary source
FLYBASE:FBgn0063491
Locus tag
Dmel_CG17534
See related
AllianceGenome:FB:FBgn0063491
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17534; CT38753; Dmel\CG17534; DmGSTE9; E9; Gst3-1; GST3-1; gste9; GSTE9
Summary
Enables glutathione transferase activity. Involved in glutathione metabolic process. Predicted to be located in cytoplasm. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See GstE9 in Genome Data Viewer
Location:
55C8-55C8; 2-85 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18409048..18409835)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14296553..14297340)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Glutathione S transferase E7 Neighboring gene Glutathione S transferase E8 Neighboring gene immune deficiency Neighboring gene Dodeca-satellite-binding protein 1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High efficiency of a double-screening method on single P-element insertion lines to identify quantitative trait mutants in Drosophila melanogaster. Martin F, et al. Genetica, 2006 Sep-Nov. PMID 17028964
  2. Small Maf functions in the maintenance of germline stem cells in the Drosophila testis. Tan SWS, et al. Redox Biol, 2018 May. PMID 29245136, Free PMC Article
  3. Epsilon glutathione transferases possess a unique class-conserved subunit interface motif that directly interacts with glutathione in the active site. Wongsantichon J, et al. Biosci Rep, 2015 Oct 20. PMID 26487708, Free PMC Article
  4. Identification of novel modifiers of Aβ toxicity by transcriptomic analysis in the fruitfly. Favrin G, et al. Sci Rep, 2013 Dec 16. PMID 24336499, Free PMC Article
  5. The genetic architecture of methotrexate toxicity is similar in Drosophila melanogaster and humans. Kislukhin G, et al. G3 (Bethesda), 2013 Aug 7. PMID 23733889, Free PMC Article

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutathione metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
glutathione S transferase E9
Names
CG17534-PA
GstE9-PA
glutathion S-transferase
NP_725784.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    18409048..18409835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166279.3 → NP_725784.1  glutathione S transferase E9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725784.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D8FT08, Q7K8X7
    Related
    FBpp0085858
    Conserved Domains (3) summary
    cd03177
    Location:92 → 209
    GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
    COG0625
    Location:4 → 201
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cd03045
    Location:4 → 76
    GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K8X7 Q7K8X7

Gene LinkOut

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