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Ugt50B3 UDP-glycosyltransferase family 50 member B3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246614, updated on 4-Jan-2025

Summary

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Official Symbol
Ugt50B3provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 50 member B3provided by FlyBase
Primary source
FLYBASE:FBgn0050438
Locus tag
Dmel_CG30438
See related
AllianceGenome:FB:FBgn0050438
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD09936; BcDNA:RE54684; CG30438; Dmel\CG30438; UGT50B3
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; embryonic head epidermis; embryonic ventral epidermis; epithelium; and plasmatocyte primordium. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8); UGT2A3 (UDP glucuronosyltransferase family 2 member A3); and UGT2B10 (UDP glucuronosyltransferase family 2 member B10). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Ugt50B3 in Genome Data Viewer
Location:
41F2-41F3; 2-55 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5496674..5549543)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1384179..1437048)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene straw Neighboring gene uncharacterized protein Neighboring gene Troponin C isoform 4 Neighboring gene uncharacterized protein Neighboring gene Fission, mitochondrial 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sex-dependent gene expression and evolution of the Drosophila transcriptome. Ranz JM, et al. Science, 2003 Jun 13. PMID 12805547
  2. Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster. Emerson JJ, et al. Science, 2008 Jun 20. PMID 18535209
  3. Molecular landscape of modified histones in Drosophila heterochromatic genes and euchromatin-heterochromatin transition zones. Yasuhara JC, et al. PLoS Genet, 2008 Jan. PMID 18208336, Free PMC Article
  4. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
  5. Unlimited Genetic Switches for Cell-Type-Specific Manipulation. Garcia-Marques J, et al. Neuron, 2019 Oct 23. PMID 31395429

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

mobile_element

  • Loc: 5497841-5498439 mobile_element_type = transposon:INE-1{}4259
  • Loc: 5501411-5502906 mobile_element_type = transposon:Tc1-2{}4466
  • Loc: 5504404-5504452 mobile_element_type = transposon:INE-1{}4262
  • Loc: 5508596-5508725 mobile_element_type = transposon:INE-1{}4265
  • Loc: 5509424-5509685 mobile_element_type = transposon:INE-1{}4266
  • Loc: 5510996-5514782 mobile_element_type = transposon:HB{}673
  • Loc: 5516434-5516521 mobile_element_type = transposon:Rt1c{}4964
  • Loc: 5516565-5516846 mobile_element_type = transposon:1360{}4373
  • Loc: 5516942-5518716 mobile_element_type = transposon:INE-1{}4271
  • Loc: 5520057-5520382 mobile_element_type = transposon:INE-1{}4275
  • Loc: 5521172-5521613 mobile_element_type = transposon:HB{}674
  • Loc: 5521650-5521724 mobile_element_type = transposon:INE-1{}4278
  • Loc: 5529323-5529350 mobile_element_type = transposon:INE-1{}4285
  • Loc: 5529611-5529959 mobile_element_type = transposon:Tc1-2{}4469
  • Loc: 5532444-5536059 mobile_element_type = transposon:Doc4{}4397
  • Loc: 5533960-5534579 mobile_element_type = transposon:gypsy8{}5023
  • Loc: 5535242-5535482 mobile_element_type = transposon:Doc{}4338
  • Loc: 5536175-5536245 mobile_element_type = transposon:Doc{}4340
  • Loc: 5540832-5541001 mobile_element_type = transposon:INE-1{}4299
  • Loc: 5543245-5547271 mobile_element_type = transposon:invader1{}677

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
UDP-glycosyltransferase family 50 member B3
Names
CG30438-PA
CG30438-PB
CG30438-PC
CG30438-PD
CG30438-PE
Ugt50B3-PA
Ugt50B3-PB
Ugt50B3-PC
Ugt50B3-PD
Ugt50B3-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5496674..5549543
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165436.3 → NP_724417.3  UDP-glycosyltransferase family 50 member B3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724417.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYL7
    Related
    FBpp0085404
    Conserved Domains (2) summary
    PHA03392
    Location:172 → 479
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    COG1819
    Location:28 → 434
    YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]

  2. NM_165435.3 → NP_724416.2  UDP-glycosyltransferase family 50 member B3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724416.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K142
    Related
    FBpp0085403
    Conserved Domains (1) summary
    PHA03392
    Location:83 → 390
    egt; ecdysteroid UDP-glucosyltransferase; Provisional

  3. NM_165437.3 → NP_724418.3  UDP-glycosyltransferase family 50 member B3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724418.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYL7
    Related
    FBpp0085405
    Conserved Domains (2) summary
    PHA03392
    Location:172 → 479
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    COG1819
    Location:28 → 434
    YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]

  4. NM_165438.3 → NP_724419.3  UDP-glycosyltransferase family 50 member B3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724419.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYL7
    Related
    FBpp0085406
    Conserved Domains (2) summary
    PHA03392
    Location:172 → 479
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    COG1819
    Location:28 → 434
    YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]

  5. NM_001273781.1 → NP_001260710.1  UDP-glycosyltransferase family 50 member B3, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260710.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYL7
    Conserved Domains (2) summary
    PHA03392
    Location:172 → 479
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    COG1819
    Location:28 → 434
    YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K142 Q7K142
Q8SYL7 Q8SYL7

Gene LinkOut

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