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Ceacam3 CEA cell adhesion molecule 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24926, updated on 27-Nov-2024

Summary

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Official Symbol
Ceacam3provided by RGD
Official Full Name
CEA cell adhesion molecule 3provided by RGD
Primary source
RGD:2333
See related
EnsemblRapid:ENSRNOG00000027607 AllianceGenome:RGD:2333
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cea; Cear; Cgm1; Cgm4; CGM4AA; Ceacam5; RATCEAA; RATCGM4AA
Summary
Predicted to be involved in T cell activation and immune response. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM21 (CEA cell adhesion molecule 21) and CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Ceacam3 in Genome Data Viewer
Location:
1q21
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (86991944..87004518)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (77863907..77876441)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79122593..79135127)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene carcinoembryonic antigen gene family 4 Neighboring gene pregnancy specific glycoprotein 16 Neighboring gene pregnancy-specific beta 1-glycoprotein Neighboring gene pregnancy-specific beta-1-glycoprotein 29

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatiotemporal expression of pregnancy-specific glycoprotein gene rnCGM1 in rat placenta. Rebstock S, et al. Dev Dyn, 1993 Nov. PMID 8136522
  2. cDNA and gene analyses imply a novel structure for a rat carcinoembryonic antigen-related protein. Rebstock S, et al. J Biol Chem, 1990 May 15. PMID 2335509
  3. Identification of a carcinoembryonic antigen gene family in the rat. Analysis of the N-terminal domains reveals immunoglobulin-like, hypervariable regions. Kodelja V, et al. J Biol Chem, 1989 Apr 25. PMID 2708349
  4. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, et al. Genome Res, 2004 Apr. PMID 15060019, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC114355

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 3
Names
Carcinoembryonic antigen gene family (CGM1)
Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein)
carcinoembryonic antigen CGM1
carcinoembryonic antigen gene family 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012702.2 → NP_036834.2  carcinoembryonic antigen-related cell adhesion molecule 3 precursor

    See identical proteins and their annotated locations for NP_036834.2

    Status: PROVISIONAL

    Source sequence(s)
    BC098921
    UniProtKB/Swiss-Prot
    Q63101, Q63111
    UniProtKB/TrEMBL
    A6J8G0, F7FFP7, Q4KLZ7
    Related
    ENSRNOP00000023663.1, ENSRNOT00000023663.4
    Conserved Domains (3) summary
    cd05774
    Location:276 → 380
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    smart00410
    Location:45 → 137
    IG_like; Immunoglobulin like
    cl11960
    Location:616 → 706
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    86991944..87004518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101138.2 → XP_038957066.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JW44
    Conserved Domains (2) summary
    cd05740
    Location:384 → 471
    IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains
    cd05774
    Location:156 → 260
    IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

  2. XM_063281070.1 → XP_063137140.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2

    Related
    ENSRNOP00000069736.2, ENSRNOT00000088393.3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q63111.1 GenPept UniProtKB/Swiss-Prot:Q63111

Gene LinkOut

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