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ssb3 DNA replication factor A subunit Ssb3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538775, updated on 18-Sep-2024

Summary

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Official Symbol
ssb3
Official Full Name
DNA replication factor A subunit Ssb3
Primary source
PomBase:SPCC23B6.05c
Locus tag
SPOM_SPCC23B6.05C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
rpa3
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Genomic context

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See ssb3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003421.2 (1281886..1282401, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ATM checkpoint kinase Neighboring gene ncRNA Neighboring gene sec14 family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 3' ssRNA-specific 3'-to-5' exonuclease

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification, gene cloning, and reconstitution of the heterotrimeric single-stranded DNA-binding protein from Schizosaccharomyces pombe. Ishiai M, et al. J Biol Chem, 1996 Aug 23. PMID 8702843
  2. Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss. Kibe T, et al. Mol Biol Cell, 2007 Jun. PMID 17429064, Free PMC Article
  3. The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks. Teixeira-Silva A, et al. Nat Commun, 2017 Dec 7. PMID 29215009, Free PMC Article
  4. Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast. Tay Z, et al. PLoS One, 2013. PMID 23365689, Free PMC Article
  5. Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant. Sánchez A, et al. Mol Cell Biol, 2012 Nov. PMID 22927644, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables damaged DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to single-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA replication, synthesis of primer ISO
Inferred from Sequence Orthology
more info
  
involved_in base-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mismatch repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic DNA replication ISO
Inferred from Sequence Orthology
more info
  
involved_in nucleotide-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in telomere maintenance NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
part_of DNA replication factor A complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of DNA replication factor A complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in chromosome, telomeric repeat region ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in site of double-strand break IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in site of double-strand break IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA replication factor A subunit Ssb3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1281886..1282401 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023118.3 → NP_588128.1  DNA replication factor A subunit Ssb3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588128.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q92374
    Conserved Domains (1) summary
    pfam08661
    Location:1 → 102
    Rep_fac-A_3; Replication factor A protein 3
Nucleotide Protein
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