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apn1 AP endonuclease, minor transcript isoform Apn1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538794, updated on 3-Dec-2024

Summary

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Official Symbol
apn1
Official Full Name
AP endonuclease, minor transcript isoform Apn1
Primary source
PomBase:SPCC622.17
Locus tag
SPOM_SPCC622.17
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See apn1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003421.2 (1435153..1436649)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Jmjc domain-containing protein Epe1 Neighboring gene ncRNA Neighboring gene siderophore-Fe(3+) transporter Str2 Neighboring gene 60S ribosomal protein eL6 Neighboring gene histone demethylase Jmj4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Schizosaccharomyces pombe encodes a mutated AP endonuclease 1. Laerdahl JK, et al. DNA Repair (Amst), 2011 Mar 7. PMID 21193357
  2. The major role of human AP-endonuclease homolog Apn2 in repair of abasic sites in Schizosaccharomyces pombe. Ribar B, et al. Nucleic Acids Res, 2004. PMID 14704348, Free PMC Article
  3. The role of Schizosaccharomyces pombe DNA repair enzymes Apn1p and Uve1p in the base excision repair of apurinic/apyrimidinic sites. Tanihigashi H, et al. Biochem Biophys Res Commun, 2006 Sep 8. PMID 16857169
  4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  5. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
NOT enables double-stranded DNA 3'-5' DNA exonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in base-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
AP endonuclease, minor transcript isoform Apn1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1435153..1436649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001431040.1 → NP_001417975.1  AP endonuclease, minor transcript isoform Apn1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P50525, Q9USI8
    UniProtKB/TrEMBL
    A0AAN2H6L4
Nucleotide Protein
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