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bpb1 zinc finger-splicing factor Bpb1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538832, updated on 18-Sep-2024

Summary

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Official Symbol
bpb1
Official Full Name
zinc finger-splicing factor Bpb1
Primary source
PomBase:SPCC962.06c
Locus tag
SPOM_SPCC962.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ods3; sf1
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Genomic context

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See bpb1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (556241..558248, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS12 Neighboring gene ncRNA Neighboring gene XP-G family protein ast1 Neighboring gene ncRNA Neighboring gene histidinol-phosphatase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23). Huang T, et al. EMBO J, 2002 Oct 15. PMID 12374752, Free PMC Article
  2. The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitro. Banerjee H, et al. RNA, 2004 Feb. PMID 14730023, Free PMC Article
  3. Mutations in the large subunit of U2AF disrupt pre-mRNA splicing, cell cycle progression and nuclear structure. Beales M, et al. Yeast, 2000 Aug. PMID 10923022
  4. Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast. Sasaki-Haraguchi N, et al. PLoS One, 2015. PMID 26302002, Free PMC Article
  5. Virtual breakdown of the nuclear envelope in fission yeast meiosis. Asakawa H, et al. Curr Biol, 2010 Nov 9. PMID 20970342

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. We propose that Cwf16p/NTC participates in the early recognition of the branch and 3' splice sites and cooperates with the SF1-U2AF59-U2AF23 complex to maintain ordered exon joining
    Title: Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of U2-type prespliceosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of commitment complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
zinc finger-splicing factor Bpb1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    556241..558248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022863.3 → NP_587871.1  zinc finger-splicing factor Bpb1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587871.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74555
    Conserved Domains (5) summary
    COG5082
    Location:269 → 400
    AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
    COG5176
    Location:17 → 306
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]
    cd02395
    Location:187 → 304
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam00098
    Location:334 → 350
    zf-CCHC; Zinc knuckle
    pfam16275
    Location:69 → 181
    SF1-HH; Splicing factor 1 helix-hairpin domain
Nucleotide Protein
Heading Accession and Version

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Research Materials