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snf22 SWI/SNF ATP-dependent chromatin remodeler Snf22 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538881, updated on 18-Sep-2024

Summary

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Official Symbol
snf22
Official Full Name
SWI/SNF ATP-dependent chromatin remodeler Snf22
Primary source
PomBase:SPCC1620.14c
Locus tag
SPOM_SPCC1620.14C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPCC830.01c
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Genomic context

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See snf22 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (2171573..2178240, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphoglycerate mutase family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1. Schwer B, et al. mBio, 2024 Jul 17. PMID 38899862, Free PMC Article
  2. Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot. Yamada T, et al. EMBO J, 2004 Apr 21. PMID 14988732, Free PMC Article
  3. Interplay between chromatin modulators and histone acetylation regulates the formation of accessible chromatin in the upstream regulatory region of fission yeast fbp1. Adachi A, et al. Genes Genet Syst, 2018 May 3. PMID 28674280
  4. Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26. Hirota K, et al. Mol Biol Cell, 2008 Mar. PMID 18199689, Free PMC Article
  5. Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex. Hayashi T, et al. Genes Cells, 2014 Jul. PMID 24774534

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.
    Title: Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.
  2. The Swi2/Snf2-like Snf22 is absolutely required for chromatin remodeling and meiotic recombination around the meiotic recombination hotspot M26. [snf22]
    Title: Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IC
Inferred by Curator
more info
  
enables ATP hydrolysis activity IC
Inferred by Curator
more info
  
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleosome array spacer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SWI/SNF complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SWI/SNF ATP-dependent chromatin remodeler Snf22

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2171573..2178240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023463.3 → NP_588472.2  SWI/SNF ATP-dependent chromatin remodeler Snf22 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588472.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94421, Q9UU97
    Conserved Domains (10) summary
    cd05519
    Location:1518 → 1620
    Bromo_SNF2; Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in transcriptional activation, it is the catalytic component of the SWI/SNF ATP-dependent chromatin remodeling complex. The protein is essential for the regulation of ...
    smart00951
    Location:428 → 463
    QLQ; QLQ is named after the conserved Gln, Leu, Gln motif
    COG0553
    Location:582 → 1345
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    COG5076
    Location:1395 → 1673
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    cd00046
    Location:889 → 1028
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00271
    Location:1187 → 1301
    Helicase_C; Helicase conserved C-terminal domain
    pfam07529
    Location:711 → 775
    HSA; HSA
    pfam14618
    Location:229 → 292
    DUF4452; Domain of unknown function (DUF4452)
    pfam14619
    Location:1398 → 1463
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    pfam15273
    Location:216 → 396
    NHS; NHS-like
Nucleotide Protein
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