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ubp16 ubiquitin hydrolase Ubp16 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538947, updated on 18-Sep-2024

Summary

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Official Symbol
ubp16
Official Full Name
ubiquitin hydrolase Ubp16
Primary source
PomBase:SPCC1682.12c
Locus tag
SPOM_SPCC1682.12C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ubp16 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (394814..397147, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene proteasome regulatory subunit Rpn8 Neighboring gene choline transmembrane transporter family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Clr6-associated factor 2 Laf2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast. Gatti L, et al. BMC Genomics, 2011 Jan 19. PMID 21247416, Free PMC Article
  2. Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA. Álvarez V, et al. Sci Rep, 2016 May 6. PMID 27151298, Free PMC Article
  3. A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. Kouranti I, et al. PLoS Biol, 2010 Sep 7. PMID 20838651, Free PMC Article
  4. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
  5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that ubp16 mutants exhibiting hypersensitivity to cisplatin.
    Title: Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables deubiquitinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal-dependent deubiquitinase activity HDA PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of protein stability IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus HDA PubMed 
is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquitin hydrolase Ubp16

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    394814..397147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022798.3 → NP_587805.1  ubiquitin hydrolase Ubp16 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587805.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74442
    Conserved Domains (2) summary
    cd02661
    Location:124 → 426
    Peptidase_C19E; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:126 → 426
    UCH; Ubiquitin carboxyl-terminal hydrolase
Nucleotide Protein
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