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ght5 plasma membrane high-affinity glucose/fructose:proton symporter Ght5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539240, updated on 18-Sep-2024

Summary

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Official Symbol
ght5
Official Full Name
plasma membrane high-affinity glucose/fructose:proton symporter Ght5
Primary source
PomBase:SPCC1235.14
Locus tag
SPOM_SPCC1235.14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ght5 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (212313..214376)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene diacylglycerol O-acyltransferase Dga1 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Iron regulates hexose transporters in Schizosaccharomyces pombe. Özkan E, et al. J Basic Microbiol, 2019 May. PMID 30730059
  2. Characterization of hexose transporter genes in the views of the chronological life span and glucose uptake in fission yeast. Maruyama T, et al. J Gen Appl Microbiol, 2023 Mar 6. PMID 35781263
  3. The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast. Nakazawa N, et al. J Cell Sci, 2018 Aug 21. PMID 30072439
  4. Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR. Saitoh S, et al. Mol Biol Cell, 2015 Jan 15. PMID 25411338, Free PMC Article
  5. Mitotic spindle formation in the absence of Polo kinase. Kim J, et al. Proc Natl Acad Sci U S A, 2022 Mar 22. PMID 35286199, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TORC2 inhibition of alpha-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose.
    Title: TORC2 inhibition of α-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose.
  2. Schizosaccharomyces pombe hexose transporter Ght5 is significantly decreased by toxic iron dose but not by non-toxic doses. Ght5 protein might play a role in sensing and signaling of iron stress.
    Title: Iron regulates hexose transporters in Schizosaccharomyces pombe.
  3. Data show that the newly synthesized glucose transport Ght5 locates preferentially at the cell tips with the aid of the target of rapamycin (TOR) complex 2 signaling.
    Title: Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables high-affinity D-glucose transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in D-glucose import IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in D-glucose import across plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in fungal-type vacuole lumen IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
plasma membrane high-affinity glucose/fructose:proton symporter Ght5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    212313..214376
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022735.3 → NP_587740.1  plasma membrane high-affinity glucose/fructose:proton symporter Ght5 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587740.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78831
    Conserved Domains (2) summary
    cd06174
    Location:10 → 451
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:11 → 467
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein
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