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dom34 translation release factor eRF1 family protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539371, updated on 18-Sep-2024

Summary

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Official Symbol
dom34
Official Full Name
translation release factor eRF1 family protein
Primary source
PomBase:SPCC18B5.06
Locus tag
SPOM_SPCC18B5.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See dom34 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003421.2 (729108..730829)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene phosphomethylpyrimidine kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleoporin Nup61 Neighboring gene isoleucine--tRNA (Ile) ligase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The stretch of C-terminal acidic amino acids of translational release factor eRF1 is a primary binding site for eRF3 of fission yeast. Ito K, et al. RNA, 1998 Aug. PMID 9701287, Free PMC Article
  2. Structure of the Dom34-Hbs1 complex and implications for no-go decay. Chen L, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20890290
  3. Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe. Guydosh NR, et al. Elife, 2017 Sep 25. PMID 28945192, Free PMC Article
  4. C-terminal interaction of translational release factors eRF1 and eRF3 of fission yeast: G-domain uncoupled binding and the role of conserved amino acids. Ebihara K, et al. RNA, 1999 Jun. PMID 10376874, Free PMC Article
  5. Structural insights into eRF3 and stop codon recognition by eRF1. Cheng Z, et al. Genes Dev, 2009 May 1. PMID 19417105, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTPase regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables translation release factor activity IC
Inferred by Curator
more info
  
Process Evidence Code Pubs
involved_in RNA surveillance IEA
Inferred from Electronic Annotation
more info
  
involved_in cytoplasmic translational termination EXP
Inferred from Experiment
more info
 PubMed 
involved_in endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nonfunctional rRNA decay IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear-transcribed mRNA catabolic process, no-go decay IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear-transcribed mRNA catabolic process, non-stop decay ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosome disassembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Dom34-Hbs1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
translation release factor eRF1 family protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    729108..730829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022927.3 → NP_587936.1  translation release factor eRF1 family protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587936.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9USL5
    Conserved Domains (1) summary
    COG1537
    Location:1 → 370
    PelA; Stalled ribosome rescue protein Dom34, pelota family [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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