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cid12 poly(A) polymerase Cid12 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539423, updated on 18-Sep-2024

Summary

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Official Symbol
cid12
Official Full Name
poly(A) polymerase Cid12
Primary source
PomBase:SPCC663.12
Locus tag
SPOM_SPCC663.12
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
csp10; csp8
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Genomic context

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See cid12 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1655646..1660080)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene splicing-associated factor Saf1 Neighboring gene NatA N-acetyltransferase subunit Naa50 Neighboring gene TRP-like ion channel protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene oxidoreductase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin. Mutazono M, et al. PLoS Genet, 2017 Feb. PMID 28231281, Free PMC Article
  2. Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance. Buscaino A, et al. EMBO J, 2013 May 2. PMID 23572080, Free PMC Article
  3. Dicer-independent primal RNAs trigger RNAi and heterochromatin formation. Halic M, et al. Cell, 2010 Feb 19. PMID 20178743, Free PMC Article
  4. Splicing factors facilitate RNAi-directed silencing in fission yeast. Bayne EH, et al. Science, 2008 Oct 24. PMID 18948543, Free PMC Article
  5. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Motamedi MR, et al. Cell, 2004 Dec 17. PMID 15607976

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cid12 has dual functions in RNAi silencing and regulating mRNA stability
    Title: Fission yeast Cid12 has dual functions in chromosome segregation and checkpoint control.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables poly(A) RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(A) RNA polymerase activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in siRNA-mediated pericentric heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA-directed RNA polymerase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
part_of nuclear RNA-directed RNA polymerase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
poly(A) polymerase Cid12

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1655646..1660080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023263.3 → NP_588273.1  poly(A) polymerase Cid12 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588273.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74518
    Conserved Domains (3) summary
    cd05402
    Location:41 → 147
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    COG5260
    Location:1 → 336
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
    pfam03828
    Location:206 → 263
    PAP_assoc; Cid1 family poly A polymerase
Nucleotide Protein
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