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for3 formin For3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539487, updated on 18-Sep-2024

Summary

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Official Symbol
for3
Official Full Name
formin For3
Primary source
PomBase:SPCC895.05
Locus tag
SPOM_SPCC895.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See for3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1002750..1007515)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SNARE protein Ufe1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene elongator complex subunit Elp2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division. Feierbach B, et al. Curr Biol, 2001 Oct 30. PMID 11696322
  2. Model of For3p-mediated actin cable assembly in fission yeast. Wang H, et al. PLoS One, 2008. PMID 19116660, Free PMC Article
  3. Dynamics of the formin for3p in actin cable assembly. Martin SG, et al. Curr Biol, 2006 Jun 20. PMID 16782006
  4. Electrical control of cell polarization in the fission yeast Schizosaccharomyces pombe. Minc N, et al. Curr Biol, 2010 Apr 27. PMID 20362451, Free PMC Article
  5. Formins determine the functional properties of actin filaments in yeast. Johnson M, et al. Curr Biol, 2014 Jul 7. PMID 24954052

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cdc12 and for3 cooperate in cytokinesis and de novo actin assembly at the division site is predominant for contractile ring formation.
    Title: The formins Cdc12 and For3 cooperate during contractile ring assembly in cytokinesis.
  2. For3 nucleates filaments 100-fold less well than Fus1, but like Cdc12, processively elongates profilin-actin at a moderate rate and lacks filament-bundling activity.
    Title: The functionally distinct fission yeast formins have specific actin-assembly properties.
  3. flow of actin cables may establish actin and For3p concentration gradients in the cytoplasm that could be important in global cell patterning.
    Title: Model of For3p-mediated actin cable assembly in fission yeast.
  4. Results indicate that Rga4p functionally interacts with For3p and has a novel function in the control of cell diameter and cell growth.
    Title: Regulation of cell diameter, For3p localization, and cell symmetry by fission yeast Rho-GAP Rga4p.
  5. For3p localizes to small dots that appear transiently at cell tips and then move away on actin cables dependent on the continuous assembly of actin in cables.
    Title: Dynamics of the formin for3p in actin cable assembly.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin filament bundle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in actin filament bundle assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin filament bundle organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in establishment or maintenance of bipolar cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic actomyosin contractile ring assembly EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitotic actomyosin contractile ring assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic actomyosin contractile ring assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein localization to mitotic actomyosin contractile ring IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell cortex of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell cortex of growing cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in mating projection tip IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mating projection tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in medial cortex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in medial cortex septin ring IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic actomyosin contractile ring IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic actomyosin contractile ring IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
formin For3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1002750..1007515
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023038.3 → NP_588046.1  formin For3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588046.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94532
    Conserved Domains (2) summary
    smart00498
    Location:846 → 1295
    FH2; Formin Homology 2 Domain
    pfam06367
    Location:307 → 511
    Drf_FH3; Diaphanous FH3 Domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials