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htb1 histone H2B Htb1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539523, updated on 18-Sep-2024

Summary

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Official Symbol
htb1
Official Full Name
histone H2B Htb1
Primary source
PomBase:SPCC622.09
Locus tag
SPOM_SPCC622.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See htb1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1412359..1413677)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene histone H2A alpha Neighboring gene exocyst complex subunit Sec5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene plasma membrane LMBR1-like multi-pass membrane protein, human LMBRD2 ortholog, implicated in signaling

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast. Naresh A, et al. J Biol Chem, 2003 Mar 14. PMID 12511578
  2. Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus. Materne P, et al. Elife, 2016 May 12. PMID 27171419, Free PMC Article
  3. In vitro reconstitution and biochemical analyses of the Schizosaccharomyces pombe nucleosome. Koyama M, et al. Biochem Biophys Res Commun, 2017 Jan 22. PMID 27890612
  4. HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast. Zofall M, et al. J Biol Chem, 2007 May 11. PMID 17363370
  5. Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein. Wang Y, et al. Mol Cell, 2009 Feb 27. PMID 19250904, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Therefore, ubiquitylated histone H2B represses gametogenesis by opposing the recruitment of RSC complex proteins at the promoter of the master regulator ste11 gene.
    Title: Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus.
  2. CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent DNA repair resection.
    Title: CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection.
  3. Transcription elongation in fission yeast is regulated by opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation.
    Title: A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin-protein adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling NAS
Non-traceable Author Statement
more info
  
involved_in double-strand break repair via homologous recombination EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of nucleosome ISM
Inferred from Sequence Model
more info
  
is_active_in nucleus HDA PubMed 
is_active_in site of double-strand break IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
histone H2B Htb1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1412359..1413677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023171.3 → NP_588181.1  histone H2B Htb1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588181.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P04913
    Conserved Domains (1) summary
    smart00427
    Location:27 → 123
    H2B; Histone H2B
Nucleotide Protein
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