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kpa1 DinB-like DNA repair polymerase kappa [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539547, updated on 18-Sep-2024

Summary

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Official Symbol
kpa1
Official Full Name
DinB-like DNA repair polymerase kappa
Primary source
PomBase:SPCC553.07c
Locus tag
SPOM_SPCC553.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
dinb; mug40; pol(kappa); pol-kappa
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Genomic context

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See kpa1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003421.2 (293376..295247)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA polymerase alpha B-subunit Neighboring gene ncRNA Neighboring gene GTPase Ria1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene oligosaccharyltransferase delta subunit Swp1 Neighboring gene ncRNA Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Postreplication gaps at UV lesions are signals for checkpoint activation. Callegari AJ, et al. Proc Natl Acad Sci U S A, 2010 May 4. PMID 20404181, Free PMC Article
  2. Rad8Rad5/Mms2-Ubc13 ubiquitin ligase complex controls translesion synthesis in fission yeast. Coulon S, et al. EMBO J, 2010 Jun 16. PMID 20453833, Free PMC Article
  3. Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication. Soriano I, et al. PLoS Genet, 2021 Jul. PMID 34228709, Free PMC Article
  4. Checkpoint activation regulates mutagenic translesion synthesis. Kai M, et al. Genes Dev, 2003 Jan 1. PMID 12514100, Free PMC Article
  5. Brc1-mediated DNA repair and damage tolerance. Sheedy DM, et al. Genetics, 2005 Oct. PMID 15972456, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-directed DNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in error-free translesion synthesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in error-prone translesion synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translesion synthesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DinB-like DNA repair polymerase kappa

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    293376..295247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022760.3 → NP_587767.2  DinB-like DNA repair polymerase kappa [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587767.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74944
    Conserved Domains (2) summary
    cd03586
    Location:133 → 471
    PolY_Pol_IV_kappa; DNA Polymerase IV/Kappa
    COG0389
    Location:130 → 474
    DinP; Nucleotidyltransferase/DNA polymerase involved in DNA repair [Replication, recombination and repair]
Nucleotide Protein
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