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nrm1 protein nrm1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539737, updated on 18-Sep-2024

Summary

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Official Symbol
nrm1
Official Full Name
protein nrm1
Primary source
PomBase:SPBC16A3.07c
Locus tag
SPOM_SPBC16A3.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See nrm1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (4285944..4288583)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Hrd1 ubiquitin ligase complex subunit Ufd1 Neighboring gene ncRNA Neighboring gene protein stm1 Neighboring gene ncRNA Neighboring gene tRNA specific adenosine deaminase Neighboring gene ncRNA Neighboring gene nucleoporin Rae1 Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein mS23

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cell Cycle-Regulated Transcription of CENP-A by the MBF Complex Ensures Optimal Level of CENP-A for Centromere Formation. Aristizabal-Corrales D, et al. Genetics, 2019 Mar. PMID 30635289, Free PMC Article
  2. Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active. Caetano C, et al. PLoS One, 2011 Feb 16. PMID 21359180, Free PMC Article
  3. The fission yeast homeodomain protein Yox1p binds to MBF and confines MBF-dependent cell-cycle transcription to G1-S via negative feedback. Aligianni S, et al. PLoS Genet, 2009 Aug. PMID 19714215, Free PMC Article
  4. DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1. de Bruin RA, et al. Proc Natl Acad Sci U S A, 2008 Aug 12. PMID 18682565, Free PMC Article
  5. Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult. Tang MY, et al. Gene, 2015 May 10. PMID 25701403

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription corepressor activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of MBF transcription complex EXP
Inferred from Experiment
more info
 PubMed 
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
protein nrm1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    4285944..4288583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023803.3 → NP_596782.1  protein nrm1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596782.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42913
    Conserved Domains (1) summary
    pfam08528
    Location:136 → 160
    Whi5; Whi5 like
Nucleotide Protein
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