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pdk1 serine/threonine protein kinase Ppk21/Pdk1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539807, updated on 18-Sep-2024

Summary

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Official Symbol
pdk1
Official Full Name
serine/threonine protein kinase Ppk21/Pdk1
Primary source
PomBase:SPBC1778.10c
Locus tag
SPOM_SPBC1778.10C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ppk21; SPBC4C3.11
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Genomic context

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See pdk1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003423.3 (3114231..3116509, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GTPase-activating protein Neighboring gene ARP2/3 actin-organizing complex subunit Arc21 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene proteasome core particle subunit beta 1 Pre3 Neighboring gene ncRNA Neighboring gene alpha-1,3-galactosyltransferase Otg3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phosphoinositide-Dependent Protein Kinases Regulate Cell Cycle Progression Through the SAD Kinase Cdr2 in Fission Yeast. Liu K, et al. Front Microbiol, 2021. PMID 35082773, Free PMC Article
  2. Roles of Pdk1p, a fission yeast protein related to phosphoinositide-dependent protein kinase, in the regulation of mitosis and cytokinesis. Bimbó A, et al. Mol Biol Cell, 2005 Jul. PMID 15857958, Free PMC Article
  3. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. Tanae K, et al. PLoS One, 2012. PMID 22291963, Free PMC Article
  4. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
  5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of attachment of mitotic spindle microtubules to kinetochore IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of mitotic division septum assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sphingolipid mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in medial cortical node IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
serine/threonine protein kinase Ppk21/Pdk1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3114231..3116509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355802.2 → NP_001342881.1  serine/threonine protein kinase Ppk21/Pdk1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O43064, Q9Y7J6
    Conserved Domains (1) summary
    cd05581
    Location:54 → 315
    STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
Nucleotide Protein
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