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tif301 translation initiation factor eIF3a [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539938, updated on 18-Sep-2024

Summary

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Official Symbol
tif301
Official Full Name
translation initiation factor eIF3a
Primary source
PomBase:SPBC17D11.05
Locus tag
SPOM_SPBC17D11.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
tif32
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Genomic context

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See tif301 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (3314331..3317452)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA primase large subunit Spp2 Neighboring gene proteasome regulatory subunit Rpn2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast homolog of murine Int-6 protein, encoded by mouse mammary tumor virus integration site, is associated with the conserved core subunits of eukaryotic translation initiation factor 3. Akiyoshi Y, et al. J Biol Chem, 2001 Mar 30. PMID 11134033
  2. Cellular stress induces cytoplasmic RNA granules in fission yeast. Nilsson D, et al. RNA, 2011 Jan. PMID 21098141, Free PMC Article
  3. Fission Yeast Asc1 Stabilizes the Interaction between Eukaryotic Initiation Factor 3a and Rps0A/uS2 for Protein Synthesis. Wang YT, et al. Mol Cell Biol, 2019 Oct 1. PMID 31285271, Free PMC Article
  4. Fission yeast mitogen-activated protein kinase Sty1 interacts with translation factors. Asp E, et al. Eukaryot Cell, 2008 Feb. PMID 18065650, Free PMC Article
  5. Activation of AP-1-dependent transcription by a truncated translation initiation factor. Jenkins CC, et al. Eukaryot Cell, 2005 Nov. PMID 16278451, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in formation of cytoplasmic translation initiation complex IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation reinitiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in cytoplasmic stress granule EXP
Inferred from Experiment
more info
 PubMed 
is_active_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic 43S preinitiation complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic 48S preinitiation complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic translation initiation factor 3 complex, eIF3e IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 3 complex, eIF3e IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic translation initiation factor 3 complex, eIF3m IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 3 complex, eIF3m IDA
Inferred from Direct Assay
more info
 PubMed 
part_of multi-eIF complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
translation initiation factor eIF3a

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3314331..3317452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022300.3 → NP_596379.1  translation initiation factor eIF3a [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596379.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74760, P78924
    Conserved Domains (1) summary
    smart00753
    Location:415 → 505
    PAM; PCI/PINT associated module
Nucleotide Protein
Heading Accession and Version

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