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rti1 DNA repair and recombination protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540121, updated on 18-Sep-2024

Summary

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Official Symbol
rti1
Official Full Name
DNA repair and recombination protein
Primary source
PomBase:SPBC119.14
Locus tag
SPOM_SPBC119.14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
rad22B
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Genomic context

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See rti1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003423.3 (746035..747734)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene tRNA-Ser Neighboring gene protein Mdm35 Neighboring gene uncharacterized protein Neighboring gene GTPase npa3 Neighboring gene ncRNA Neighboring gene metalloendopeptidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair. Octobre G, et al. Genetics, 2008 Apr. PMID 18430957, Free PMC Article
  2. Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures. de Vries FA, et al. Mutat Res, 2007 Feb 3. PMID 17208257
  3. Characterization of RAD52 homologs in the fission yeast Schizosaccharomyces pombe. van den Bosch M, et al. Mutat Res, 2001 Jan 5. PMID 11104907
  4. A double-strand break repair component is essential for S phase completion in fission yeast cell cycling. Suto K, et al. Mol Biol Cell, 1999 Oct. PMID 10512870, Free PMC Article
  5. Differential expression and requirements for Schizosaccharomyces pombe RAD52 homologs in DNA repair and recombination. van den Bosch M, et al. Nucleic Acids Res, 2002 Mar 15. PMID 11884628, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The most important function of Rad22 and Rti1 in S. pombe meiosis is repair of double-strand breaks with involvement of the sister chromatids.
    Title: The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair.
  2. rad54 and the RAD52 orthologs rad22A and rad22B are epistatic for the repair of double-strand breaks in DNA.
    Title: Inactivation of RAD52 aggravates RAD54 defects in mice but not in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA strand exchange activity ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables single-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA recombinase assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in double-strand break repair via single-strand annealing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nuclear chromosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DNA repair and recombination protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    746035..747734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021203.2 → NP_595296.1  DNA repair and recombination protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595296.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42905
    Conserved Domains (1) summary
    COG5055
    Location:1 → 371
    RAD52; Recombination DNA repair protein (RAD52 pathway) [Replication, recombination and repair]
Nucleotide Protein
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