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srb7 mediator complex subunit Med21 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540209, updated on 18-Sep-2024

Summary

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Official Symbol
srb7
Official Full Name
mediator complex subunit Med21
Primary source
PomBase:SPBC1604.10
Locus tag
SPOM_SPBC1604.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
med21
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Genomic context

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See srb7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (3912870..3913638, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F0-ATPase subunit F Neighboring gene ncRNA Neighboring gene tRNA-Leu Neighboring gene ncRNA Neighboring gene exoribonuclease Rex4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
  2. Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nozawa K, et al. Nature, 2017 May 11. PMID 28467824
  3. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
  4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables transcription coactivator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription initiation by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mediator complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mediator complex subunit Med21

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3912870..3913638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022551.3 → NP_596630.1  mediator complex subunit Med21 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596630.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94376
    Conserved Domains (1) summary
    pfam11221
    Location:1 → 130
    Med21; Subunit 21 of Mediator complex
Nucleotide Protein
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