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ctu1 cytosolic thiouridylase subunit Ctu1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540314, updated on 18-Sep-2024

Summary

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Official Symbol
ctu1
Official Full Name
cytosolic thiouridylase subunit Ctu1
Primary source
PomBase:SPBC2G5.03
Locus tag
SPOM_SPBC2G5.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ctu1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2581935..2583104)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene CK2 family regulatory subunit protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene COPII-coated vesicle-associated protein Erv41 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity. Dewez M, et al. Proc Natl Acad Sci U S A, 2008 Apr 8. PMID 18391219, Free PMC Article
  2. Translational control of cell division by Elongator. Bauer F, et al. Cell Rep, 2012 May 31. PMID 22768388, Free PMC Article
  3. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article
  4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
  5. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to tRNA-uridine 2-sulfurtransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein urmylation IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA wobble position uridine thiolation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA wobble position uridine thiolation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of cytosolic tRNA wobble base thiouridylase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic tRNA wobble base thiouridylase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
cytosolic thiouridylase subunit Ctu1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2581935..2583104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021975.3 → NP_596064.1  cytosolic thiouridylase subunit Ctu1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596064.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94282
    Conserved Domains (3) summary
    TIGR00269
    Location:206 → 308
    TIGR00269; TIGR00269 family protein
    COG0037
    Location:29 → 330
    TilS; tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]
    cd01993
    Location:53 → 241
    Alpha_ANH_like_II; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
Nucleotide Protein
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