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uve1 endonuclease Uve1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540345, updated on 18-Sep-2024

Summary

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Official Symbol
uve1
Official Full Name
endonuclease Uve1
Primary source
PomBase:SPBC19C7.09c
Locus tag
SPOM_SPBC19C7.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
uvde
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Genomic context

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See uve1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2837572..2839585, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA-splicing endonuclease catalytic subunit Sen34 Neighboring gene ncRNA Neighboring gene tRNA methyltransferase Ppm2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene integral nuclear inner membrane protein Bqt4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression, purification, and characterization of ultraviolet DNA endonuclease from Schizosaccharomyces pombe. Kaur B, et al. Biochemistry, 1998 Aug 18. PMID 9708997
  2. A Uve1p-mediated mismatch repair pathway in Schizosaccharomyces pombe. Kaur B, et al. Mol Cell Biol, 1999 Jul. PMID 10373519, Free PMC Article
  3. A new ATP-independent DNA endonuclease from Schizosaccharomyces pombe that recognizes cyclobutane pyrimidine dimers and 6-4 photoproducts. Bowman KK, et al. Nucleic Acids Res, 1994 Aug 11. PMID 8065916, Free PMC Article
  4. Alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe operates both in nucleus and in mitochondria. Yasuhira S, et al. J Biol Chem, 2000 Apr 21. PMID 10766807
  5. Ultraviolet damage endonuclease (Uve1p): a structure and strand-specific DNA endonuclease. Kaur B, et al. Biochemistry, 2000 May 16. PMID 10801329

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Although Apn1p and Uve1p incised the oligonucleotide containing an AP site analogue, these enzymes could not initiate repair of the AP sites in vivo.
    Title: The role of Schizosaccharomyces pombe DNA repair enzymes Apn1p and Uve1p in the base excision repair of apurinic/apyrimidinic sites.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 5' deoxyribonuclease (pyrimidine dimer) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables endonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables heteroduplex DNA loop binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in UV-damage excision repair IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in UV-damage excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in base-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mismatch repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
  
involved_in pyrimidine dimer repair IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial chromosome IC
Inferred by Curator
more info
  
is_active_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
endonuclease Uve1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2837572..2839585 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022085.3 → NP_596165.1  endonuclease Uve1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596165.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P87339, Q10988
    Conserved Domains (1) summary
    TIGR00629
    Location:245 → 552
    uvde; UV damage endonuclease UvdE
Nucleotide Protein
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