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muk1 guanyl-nucleotide exchange factor Muk1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540384, updated on 18-Sep-2024

Summary

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Official Symbol
muk1
Official Full Name
guanyl-nucleotide exchange factor Muk1
Primary source
PomBase:SPBC29A10.11c
Locus tag
SPOM_SPBC29A10.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
vps902; vps9b
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Genomic context

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See muk1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (2563477..2565609, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CAF1 family ribonuclease Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase Dbl8 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene oxidative stress transcription coactivator/ribosome recycling protein Oxs1 Neighboring gene F0-ATPase subunit D

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Coordinated regulation by two VPS9 domain-containing guanine nucleotide exchange factors in small GTPase Rab5 signaling pathways in fission yeast. Tsukamoto Y, et al. Biochem Biophys Res Commun, 2015 Mar 20. PMID 25686494
  2. CUE domain-containing protein Vps901 is required for vacuolar protein transport in Schizosaccharomyces pombe. Nakase M, et al. Biosci Biotechnol Biochem, 2012. PMID 22484924
  3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Deletion of both vps901 and vps902 genes completely abolished the mating process and responses to various stresses.
    Title: Coordinated regulation by two VPS9 domain-containing guanine nucleotide exchange factors in small GTPase Rab5 signaling pathways in fission yeast.
  2. Deletion of vps902(+) had no effect on vacuolar transport, suggesting that only Vps901p functions in vacuolar protein transport in S. pombe.
    Title: CUE domain-containing protein Vps901 is required for vacuolar protein transport in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
guanyl-nucleotide exchange factor Muk1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2563477..2565609 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355777.2 → NP_001342780.1  guanyl-nucleotide exchange factor Muk1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    D2CFN7, O94388
    Conserved Domains (1) summary
    pfam02204
    Location:173 → 274
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
Nucleotide Protein
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