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iml1 GATOR1-SEACIT GTPase activating complex subunit Iml1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540559, updated on 18-Sep-2024

Summary

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Official Symbol
iml1
Official Full Name
GATOR1-SEACIT GTPase activating complex subunit Iml1
Primary source
PomBase:SPBC26H8.04c
Locus tag
SPOM_SPBC26H8.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See iml1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3948910..3953809, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphatidylethanolamine N-methyltransferase Cho2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase. Fukuda T, et al. Elife, 2021 Feb 3. PMID 33534698, Free PMC Article
  2. Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases. Chia KH, et al. Elife, 2017 Dec 4. PMID 29199950, Free PMC Article
  3. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTPase activator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of TORC1 signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of TORC1 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of autophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of GATOR1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GATOR1 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in vacuolar membrane EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
GATOR1-SEACIT GTPase activating complex subunit Iml1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3948910..3953809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022567.3 → NP_596645.1  GATOR1-SEACIT GTPase activating complex subunit Iml1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596645.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74788
    Conserved Domains (2) summary
    cd04449
    Location:1107 → 1189
    DEP_DEPDC5-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC5-like proteins. DEPDC5, in human also known as KIAA0645, is a DEP domain containing protein of unknown function.
    pfam12257
    Location:127 → 425
    DUF3608; Protein of unknown function (DUF3608)
Nucleotide Protein
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