U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sid4 SIN component scaffold protein Sid4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540650, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
sid4
Official Full Name
SIN component scaffold protein Sid4
Primary source
PomBase:SPBC244.01c
Locus tag
SPOM_SPBC244.01C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See sid4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (4360626..4363926)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U3 snoRNP-associated protein Utp6 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene mitochondrial 54S ribosomal protein mL57 Neighboring gene argininosuccinate lyase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Relief of the Dma1-mediated checkpoint requires Dma1 autoubiquitination and dynamic localization. Jones CM, et al. Mol Biol Cell, 2018 Sep 1. PMID 29975113, Free PMC Article
  2. Fission yeast Dma1 requires RING domain dimerization for its ubiquitin ligase activity and mitotic checkpoint function. Johnson AE, et al. J Biol Chem, 2012 Jul 27. PMID 22669973, Free PMC Article
  3. The spindle pole body protein Cdc11p links Sid4p to the fission yeast septation initiation network. Tomlin GC, et al. Mol Biol Cell, 2002 Apr. PMID 11950932, Free PMC Article
  4. Mug27 is a meiosis-specific protein kinase that functions in fission yeast meiosis II and sporulation. Ohtaka A, et al. J Cell Sci, 2008 May 1. PMID 18411246
  5. Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast. Chang L, et al. Proc Natl Acad Sci U S A, 2000 May 9. PMID 10805785, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Signals from Sid4 contribute to the Cut12 mitotic commitment switch.
    Title: Dialogue between centrosomal entrance and exit scaffold pathways regulates mitotic commitment.
  2. Sid4 ubiquitination by Dma1 delays recruitment of the Polo-like kinase and SIN activator, Plo1, to spindle pole bodies, and is required to prevent cytokinesis during a mitotic checkpoint arrest.
    Title: Dma1 ubiquitinates the SIN scaffold, Sid4, to impede the mitotic localization of Plo1 kinase.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables signaling adaptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cytokinesis EXP
Inferred from Experiment
more info
 PubMed 
involved_in negative regulation of septation initiation signaling EXP
Inferred from Experiment
more info
 PubMed 
involved_in septation initiation signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in meiotic spindle pole EXP
Inferred from Experiment
more info
 PubMed 
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in outer plaque of mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
SIN component scaffold protein Sid4

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    4360626..4363926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023834.3 → NP_596814.1  SIN component scaffold protein Sid4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596814.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O60187
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials