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lsm5 U6 snRNP-associated protein Lsm5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540723, updated on 18-Sep-2024

Summary

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Official Symbol
lsm5
Official Full Name
U6 snRNP-associated protein Lsm5
Primary source
PomBase:SPBC20F10.09
Locus tag
SPOM_SPBC20F10.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lsm5 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (3301295..3302135)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase II nuclear import protein Rtp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pho85 family cyclin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the LSm657 complex: an assembly intermediate of the LSm1-7 and LSm2-8 rings. Mund M, et al. J Mol Biol, 2011 Nov 25. PMID 22001694
  2. Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe. Wu D, et al. PLoS One, 2012. PMID 22615807, Free PMC Article
  3. Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast. Páez-Moscoso DJ, et al. Nat Commun, 2018 Feb 8. PMID 29422664, Free PMC Article
  4. Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Montemayor EJ, et al. RNA, 2020 Oct. PMID 32518066, Free PMC Article
  5. LARP7 family proteins have conserved function in telomerase assembly. Collopy LC, et al. Nat Commun, 2018 Feb 8. PMID 29422501, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables U2 snRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables poly(U) RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in telomerase holoenzyme complex assembly TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex EXP
Inferred from Experiment
more info
 PubMed 
part_of Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Lsm2-8 complex EXP
Inferred from Experiment
more info
 PubMed 
part_of U2 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U5 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U6 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus HDA PubMed 
part_of sno(s)RNA-containing ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of telomerase holoenzyme complex EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
U6 snRNP-associated protein Lsm5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3301295..3302135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022294.3 → NP_596373.1  U6 snRNP-associated protein Lsm5 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596373.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42978
    Conserved Domains (1) summary
    cd01732
    Location:4 → 77
    LSm5; Like-Sm protein 5
Nucleotide Protein
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