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gea1 guanyl-nucleotide exchange factor [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540746, updated on 18-Sep-2024

Summary

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Official Symbol
gea1
Official Full Name
guanyl-nucleotide exchange factor
Primary source
PomBase:SPBC211.03c
Locus tag
SPOM_SPBC211.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See gea1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3875125..3879920, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene protein Cwf3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MCM complex subunit Mcm6 Neighboring gene ncRNA Neighboring gene splicing factor 3B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast. Eckler AM, et al. PLoS One, 2013. PMID 23457617, Free PMC Article
  2. Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast. Ikebe C, et al. Biosci Biotechnol Biochem, 2011. PMID 22146723
  3. SR protein kinases promote splicing of nonconsensus introns. Lipp JJ, et al. Nat Struct Mol Biol, 2015 Aug. PMID 26167880
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. gea1 in regulation of septum breakdown and establish S. pombe as a model system to explore GBF1/GEA function in cytokinesis
    Title: Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in Golgi to plasma membrane protein transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
  
involved_in signaling NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
guanyl-nucleotide exchange factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3875125..3879920 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022534.3 → NP_596613.1  guanyl-nucleotide exchange factor [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596613.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7R8
    Conserved Domains (3) summary
    COG5307
    Location:289 → 1303
    COG5307; Guanine-nucleotide exchange factor, contains Sec7 domain [General function prediction only]
    pfam01369
    Location:548 → 732
    Sec7; Sec7 domain
    pfam12783
    Location:287 → 475
    Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
Nucleotide Protein
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Gene LinkOut

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