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met17 homocysteine synthase Met17 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540849, updated on 14-Nov-2024

Summary

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Official Symbol
met17
Official Full Name
homocysteine synthase Met17
Primary source
PomBase:SPBC428.11
Locus tag
SPOM_SPBC428.11
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
cys2
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Genomic context

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See met17 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (465380..467247)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene tRNA-His Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene peptidyl-prolyl cis-trans isomerase E Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sulphur amino acid synthesis in Schizosaccharomyces pombe represents a specific variant of sulphur metabolism in fungi. Brzywczy J, et al. Yeast, 2002 Jan 15. PMID 11754480
  2. O-Acetylhomoserine sulfhydrylase of the fission yeast Schizosaccharomyces pombe: partial purification, characterization, and its probable role in homocysteine biosynthesis. Yamagata S. J Biochem, 1984 Nov. PMID 6526818
  3. Multiple fungal enzymes possess cysteine synthase activity in vitro. Brzywczy J, et al. Res Microbiol, 2007 Jun. PMID 17482430
  4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables O-acetylhomoserine sulfhydrylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables O-acetylhomoserine sulfhydrylase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables cysteine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cysteine synthase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables cysteine synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 'de novo' L-methionine biosynthetic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in L-homocysteine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-homocysteine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cysteine biosynthetic process from serine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cysteine biosynthetic process via cystathionine IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
homocysteine synthase Met17

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    465380..467247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021096.3 → NP_595189.1  homocysteine synthase Met17 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595189.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13326
    Conserved Domains (2) summary
    PRK08776
    Location:7 → 429
    PRK08776; cystathionine gamma-synthase; Provisional
    TIGR01326
    Location:7 → 427
    OAH_OAS_sulfhy; OAH/OAS sulfhydrylase
Nucleotide Protein
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