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nse5 Smc5-6 complex non-SMC subunit Nse5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540911, updated on 18-Sep-2024

Summary

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Official Symbol
nse5
Official Full Name
Smc5-6 complex non-SMC subunit Nse5
Primary source
PomBase:SPBC651.10
Locus tag
SPOM_SPBC651.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See nse5 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1257903..1259192)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase III complex large subunit Rpc1 Neighboring gene ncRNA Neighboring gene RNA polymerase II-associated Paf1 complex protein Neighboring gene ncRNA Neighboring gene AP-3 adaptor complex subunit Apm3 Neighboring gene protein dbl7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Smc5-Smc6 DNA repair complex. bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits. Palecek J, et al. J Biol Chem, 2006 Dec 1. PMID 17005570
  2. A role of the Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6. Vondrova L, et al. Sci Rep, 2020 Jun 16. PMID 32546830, Free PMC Article
  3. Brc1 Promotes the Focal Accumulation and SUMO Ligase Activity of Smc5-Smc6 during Replication Stress. Oravcová M, et al. Mol Cell Biol, 2019 Jan 15. PMID 30348841, Free PMC Article
  4. Meiotic DNA joint molecule resolution depends on Nse5-Nse6 of the Smc5-Smc6 holocomplex. Wehrkamp-Richter S, et al. Nucleic Acids Res, 2012 Oct. PMID 22855558, Free PMC Article
  5. Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant. Sánchez A, et al. Mol Cell Biol, 2012 Nov. PMID 22927644, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables chromatin-protein adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in double-strand break repair EXP
Inferred from Experiment
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Smc5-Smc6 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Smc5-6 complex non-SMC subunit Nse5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1257903..1259192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021418.3 → NP_595508.1  Smc5-6 complex non-SMC subunit Nse5 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94668
    Conserved Domains (1) summary
    pfam08691
    Location:2 → 369
    Nse5; DNA repair proteins Nse5 and Nse6
Nucleotide Protein
Heading Accession and Version

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