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hsp16 heat shock protein Hsp16 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540977, updated on 14-Nov-2024

Summary

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Official Symbol
hsp16
Official Full Name
heat shock protein Hsp16
Primary source
PomBase:SPBC3E7.02c
Locus tag
SPOM_SPBC3E7.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See hsp16 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2660139..2660992, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene Prp19 complex WD repeat protein Prp17 Neighboring gene 1-phosphatidylinositol-3-phosphate 5-kinase Fab1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene synembryn ric8-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interaction of a small heat shock protein of the fission yeast, Schizosaccharomyces pombe, with a denatured protein at elevated temperature. Hirose M, et al. J Biol Chem, 2005 Sep 23. PMID 16055437
  2. Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe. Hanazono Y, et al. Structure, 2013 Feb 5. PMID 23273429
  3. Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe. Yoshida J, et al. Cell Struct Funct, 2005 Feb. PMID 15840944
  4. Formation of non-toxic Aβ fibrils by small heat shock protein under heat-stress conditions. Sakono M, et al. Biochem Biophys Res Commun, 2013 Jan 25. PMID 23261462
  5. Characterization of a sHsp of Schizosaccharomyces pombe, SpHsp15.8, and the implication of its functional mechanism by comparison with another sHsp, SpHsp16.0. Sugino C, et al. Proteins, 2009 Jan. PMID 18543332

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The HSP16 monomers show nonequivalence in the interaction with neighboring monomers and conformations of the N- and C-terminal regions.
    Title: Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe.
  2. SpHsp16.0 is likely to interact with denatured CS in the dissociated state, while SpHsp15.8 is likely to interact with CS in a large complex.
    Title: Characterization of a sHsp of Schizosaccharomyces pombe, SpHsp15.8, and the implication of its functional mechanism by comparison with another sHsp, SpHsp16.0.
  3. SpHsp16.0 protects citrate synthase from thermal aggregation at 45 degrees C with high efficiency
    Title: Interaction of a small heat shock protein of the fission yeast, Schizosaccharomyces pombe, with a denatured protein at elevated temperature.
  4. Hsp16 is required for thermotolerance in nuclear mRNA export in Schizosaccharomyces.
    Title: Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein folding chaperone IDA
Inferred from Direct Assay
more info
 PubMed 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to heat IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to misfolded protein IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to unfolded protein IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein complex oligomerization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to heat IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to hydrogen peroxide IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to salt stress IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in protein aggregate center IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
heat shock protein Hsp16

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2660139..2660992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022007.2 → NP_596091.1  heat shock protein Hsp16 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596091.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14368
    Conserved Domains (1) summary
    COG0071
    Location:1 → 143
    IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
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