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gnd1 phosphogluconate dehydrogenase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541146, updated on 18-Sep-2024

Summary

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Official Symbol
gnd1
Official Full Name
phosphogluconate dehydrogenase
Primary source
PomBase:SPBC660.16
Locus tag
SPOM_SPBC660.16
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See gnd1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003423.3 (230322..233218)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene cleavage factor complex subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene autophagy-associated protein Atg2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification and kinetic characterization of 6-phosphogluconate dehydrogenase from Schizosaccharomyces pombe. Tsai CS, et al. Biochem Cell Biol, 1998. PMID 10099784
  2. Kinetic studies of gluconate pathway enzymes from Schizosaccharomyces pombe. Tsai CS, et al. Arch Biochem Biophys, 1995 Jan 10. PMID 7840612
  3. Carbon-13 NMR studies and purification of gluconate pathway enzymes from Schizosaccharomyces pombe. Tsai CS, et al. Arch Biochem Biophys, 1995 Jan 10. PMID 7840611
  4. Repression of enzymes of the pentose phosphate pathway by glucose in fission yeast. Mehta S, et al. FEBS Lett, 1998 Dec 4. PMID 9872416
  5. Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1. Kilchert C, et al. Cell Rep, 2015 Dec 22. PMID 26670050, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables NADP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphogluconate dehydrogenase (decarboxylating) activity EXP
Inferred from Experiment
more info
 PubMed 
enables phosphogluconate dehydrogenase (decarboxylating) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphogluconate dehydrogenase (decarboxylating) activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in D-gluconate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in D-gluconate catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glycolytic process via Entner-Doudoroff Pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pentose-phosphate shunt, oxidative branch EXP
Inferred from Experiment
more info
 PubMed 
involved_in pentose-phosphate shunt, oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pentose-phosphate shunt, oxidative branch IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
phosphogluconate dehydrogenase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    230322..233218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021002.3 → NP_595095.1  phosphogluconate dehydrogenase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595095.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78812, Q9UQW5
    Conserved Domains (3) summary
    COG0362
    Location:5 → 484
    Gnd; 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]
    pfam00393
    Location:183 → 478
    6PGD; 6-phosphogluconate dehydrogenase, C-terminal domain
    pfam03446
    Location:7 → 179
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
Nucleotide Protein
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