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prp17 Prp19 complex WD repeat protein Prp17 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541168, updated on 18-Sep-2024

Summary

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Official Symbol
prp17
Official Full Name
Prp19 complex WD repeat protein Prp17
Primary source
PomBase:SPBC6B1.10
Locus tag
SPOM_SPBC6B1.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See prp17 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003423.3 (2651594..2659395)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mre11 complex BRCT domain subunit Nbs1 Neighboring gene 1-phosphatidylinositol-3-phosphate 5-kinase Fab1 Neighboring gene ncRNA Neighboring gene heat shock protein Hsp16

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression. Saha D, et al. Biochem Biophys Res Commun, 2012 Aug 3. PMID 22789856
  2. Splicing of branchpoint-distant exons is promoted by Cactin, Tls1 and the ubiquitin-fold-activated Sde2. Anil AT, et al. Nucleic Acids Res, 2022 Sep 23. PMID 36095128, Free PMC Article
  3. The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Aronica L, et al. Nucleic Acids Res, 2016 Feb 29. PMID 26682798, Free PMC Article
  4. Structure of a yeast spliceosome at 3.6-angstrom resolution. Yan C, et al. Science, 2015 Sep 11. PMID 26292707
  5. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. genetic interactions between BUD31 and PRP17 were examined.
    Title: Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Prp19 complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of post-mRNA release spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Prp19 complex WD repeat protein Prp17

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2651594..2659395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355781.2 → NP_001342709.1  Prp19 complex WD repeat protein Prp17 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O43071
    Conserved Domains (2) summary
    cd00200
    Location:258 → 558
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:269 → 308
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
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