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prp1 U4/U6 x U5 tri-snRNP complex subunit Prp1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541185, updated on 18-Sep-2024

Summary

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Official Symbol
prp1
Official Full Name
U4/U6 x U5 tri-snRNP complex subunit Prp1
Primary source
PomBase:SPBC6B1.07
Locus tag
SPOM_SPBC6B1.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
zer1
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Genomic context

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See prp1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2641921..2644897)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 2-oxoglutarate and Fe(2+) dioxygenase domain-containing protein 1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The prp1+ gene required for pre-mRNA splicing in Schizosaccharomyces pombe encodes a protein that contains TPR motifs and is similar to Prp6p of budding yeast. Urushiyama S, et al. Genetics, 1997 Sep. PMID 9286671, Free PMC Article
  2. Pre-mRNA splicing mutants of Schizosaccharomyces pombe. Potashkin J, et al. EMBO J, 1989 Feb. PMID 2721492, Free PMC Article
  3. Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly. Banerjee S, et al. Mol Cell Biol, 2013 Aug. PMID 23754748, Free PMC Article
  4. Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor. Schwelnus W, et al. EMBO Rep, 2001 Jan. PMID 11252721, Free PMC Article
  5. Mutant allele of rna14 in fission yeast affects pre-mRNA splicing. Yadav S, et al. J Genet, 2016 Jun. PMID 27350684

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spliceosomal tri-snRNP complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U4/U6 x U5 tri-snRNP complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
U4/U6 x U5 tri-snRNP complex subunit Prp1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2641921..2644897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022000.3 → NP_596086.1  U4/U6 x U5 tri-snRNP complex subunit Prp1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596086.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q12381
    Conserved Domains (3) summary
    smart00386
    Location:384 → 414
    HAT; HAT (Half-A-TPR) repeats
    sd00006
    Location:678 → 708
    TPR; TPR repeat [structural motif]
    pfam06424
    Location:13 → 157
    PRP1_N; PRP1 splicing factor, N-terminal
Nucleotide Protein
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