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msy2 MS ion channel protein 2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541425, updated on 18-Sep-2024

Summary

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Official Symbol
msy2
Official Full Name
MS ion channel protein 2
Primary source
PomBase:SPAC2C4.17c
Locus tag
SPOM_SPAC2C4.17C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See msy2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4288009..4291761, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene UBX domain protein Ubx2 Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS8 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mechanosensitive channels Msy1 and Msy2 are required for maintaining organelle integrity upon hypoosmotic shock in Schizosaccharomyces pombe. Nakayama Y, et al. FEMS Yeast Res, 2014 Sep. PMID 25041276
  2. Organellar mechanosensitive channels in fission yeast regulate the hypo-osmotic shock response. Nakayama Y, et al. Nat Commun, 2012. PMID 22910366
  3. Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast. Burr R, et al. J Biol Chem, 2017 Sep 29. PMID 28821619, Free PMC Article
  4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Msy1 and Msy2 regulate intracellular Ca(2+) and cell volume for survival upon hypo-osmotic shock.
    Title: Organellar mechanosensitive channels in fission yeast regulate the hypo-osmotic shock response.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables mechanosensitive monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell volume homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cortical endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
MS ion channel protein 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4288009..4291761 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019949.3 → NP_594520.1  MS ion channel protein 2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594520.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14050
    Conserved Domains (2) summary
    COG0668
    Location:442 → 623
    MscS; Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]
    pfam00924
    Location:445 → 644
    MS_channel; Mechanosensitive ion channel
Nucleotide Protein
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