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ppk11 PAK-like kinase Ppk11 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541473, updated on 18-Sep-2024

Summary

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Official Symbol
ppk11
Official Full Name
PAK-like kinase Ppk11
Primary source
PomBase:SPAC2C4.14c
Locus tag
SPOM_SPAC2C4.14C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ppk11 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4282491..4284554, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA 2'-phosphotransferase Tpt1 Neighboring gene ncRNA Neighboring gene V-type ATPase V0 subunit c'' Neighboring gene ncRNA Neighboring gene UBX domain protein Ubx2 Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast germinal center (GC) kinase Ppk11 interacts with Pmo25 and plays an auxiliary role in concert with the morphogenesis Orb6 network (MOR) in cell morphogenesis. Goshima T, et al. J Biol Chem, 2010 Nov 5. PMID 20826805, Free PMC Article
  2. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. Tanae K, et al. PLoS One, 2012. PMID 22291963, Free PMC Article
  3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
  4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. both interaction of Ppk11 with Pmo25 and Ppk11 kinase activity are critical for efficient cell separation.
    Title: Fission yeast germinal center (GC) kinase Ppk11 interacts with Pmo25 and plays an auxiliary role in concert with the morphogenesis Orb6 network (MOR) in cell morphogenesis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to cell division site IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of establishment or maintenance of bipolar cell polarity regulating cell shape IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of establishment or maintenance of bipolar cell polarity regulating cell shape IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in septum digestion after cytokinesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in division septum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
PAK-like kinase Ppk11

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4282491..4284554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019946.3 → NP_594517.1  PAK-like kinase Ppk11 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594517.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14047
    Conserved Domains (2) summary
    smart00220
    Location:6 → 258
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06609
    Location:4 → 278
    STKc_MST3_like; Catalytic domain of Mammalian Ste20-like protein kinase 3-like Serine/Threonine Kinases
Nucleotide Protein
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